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Nigella Sativa study #2 of 4   All Outcomes
1/31 Early treatment study
Al-Haidari et al., Indian Journal of Forensic Medicine & Toxicology, 15:3 (preprint 1/2021) (Peer Reviewed)
Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City / Iraq
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Open-label RCT with 419 patients in Iraq, 160 treated with Nigella Sativa, showing lower mortality and severe cases with treatment.
Al-Haidari et al., 1/31/2021, Randomized Controlled Trial, Iraq, Middle East, peer-reviewed, 3 authors.
risk of death, 95.8% lower, RR 0.04, p = 0.001, treatment 0 of 160 (0.0%), control 14 of 259 (5.4%), continuity correction due to zero event (with reciprocal of the contrasting arm).
risk of COVID-19 severe case, 92.6% lower, RR 0.07, p < 0.001, treatment 2 of 160 (1.2%), control 44 of 259 (17.0%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
All 4 studies   All Outcomes
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