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Nigella Sativa study #10   All Outcomes
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Hospitalization 75% Imp. Relative Risk, 95% CI Recovery 43% Koshak: Nigella sativa for the treatment of COVID-19: An open-la.. c19ns.com/koshak.html Favors nigella sativa Favors control
8/15 Early treatment study
Koshak et al., Complementary Therapies in Medicine, doi:10.1016/j.ctim.2021.102769 (Peer Reviewed)
Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial
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RCT 183 mild COVID-19 outpatients in Saudi Arabia, 91 treated with Nigella Sativa, showing lower hospitalization and faster recovery with treatment. NCT04401202.
500mg Nigella sativa oil (MARNYS Cuminmar) twice daily for 10 days.
risk of hospitalization, 74.7% lower, RR 0.25, p = 0.37, treatment 1 of 91 (1.1%), control 4 of 92 (4.3%).
risk of no recovery, 42.7% lower, RR 0.57, p < 0.001, treatment 34 of 91 (37.4%), control 60 of 92 (65.2%).
Koshak et al., 8/15/2021, Randomized Controlled Trial, Saudi Arabia, Middle East, peer-reviewed, 10 authors.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical significance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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