Setayesh, 79 patient nigella sativa late treatment RCT: 27% lower need for oxygen therapy [p=0.007] and 29% shorter hospitalization [p<0.0001] https://c19p.org/setayesh
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Efficacy of a Persian herbal medicine compound on coronavirus disease 2019 (COVID-19): a randomized clinical trial
et al., Integrative Medicine Research, doi:10.1016/j.imr.2022.100869, IRCT20200330046899N1
Small RCT 41 patients treated with nigella sativa, glycyrrhiza glabra, punica granatum, and rheum palmatum, and 41 control patients, showing shorter hospitalization with treatment.
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risk of death, 7.9% higher, RR 1.08, p = 1.00, treatment 1 of 38 (2.6%), control 1 of 41 (2.4%).
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oxygen time, 26.8% lower, relative time 0.73, p = 0.007, treatment mean 3.0 (±1.6) n=38, control mean 4.1 (±1.9) n=41.
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hospitalization time, 28.7% lower, relative time 0.71, p < 0.001, treatment mean 5.7 (±1.9) n=38, control mean 8.0 (±1.8) n=41.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Setayesh et al., 6/3/2022, Randomized Controlled Trial, Iran, peer-reviewed, mean age 59.1, 7 authors, study period June 2020 - September 2020, this trial uses multiple treatments in the treatment arm (combined with glycyrrhiza glabra, punica granatum, and rheum palmatum) - results of individual treatments may vary, trial IRCT20200330046899N1.
Contact:
hasheminasab@zaums.ac.ir, hashemifa67@gmail.com.
Late treatment
is less effective
is less effective
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