• Statistically significant improvements are seen for mortality, hospitalization, recovery, cases, and viral clearance. 5 studies from 4 independent teams in 4 different countries show statistically significant improvements in isolation (3 for the most serious outcome).
• Meta analysis using the most serious outcome reported shows 61% [40‑75%] improvement. Results are better for Randomized Controlled Trials, similar after exclusions, and similar for peer-reviewed studies. Early treatment is more effective than late treatment.
• While many treatments have some level of efficacy, they do not replace vaccines and other measures to avoid infection. Only 29% of nigella sativa studies show zero events in the treatment arm. Multiple treatments are typically used in combination, and other treatments may be more effective.
• No treatment, vaccine, or intervention is 100% available and effective for all variants. All practical, effective, and safe means should be used. Denying the efficacy of treatments increases mortality, morbidity, collateral damage, and endemic risk.
• All data to reproduce this paper and sources are in the appendix.
Covid Analysis et al., 6/22/2022, preprint, 1 author.